Hong Liang Selected Research

Cisplatin (Platino)

3/2024	Designing a Mitochondria-Targeted Theranostic Cyclometalated Iridium(III) Complex: Overcoming Cisplatin Resistance and Inhibiting Tumor Metastasis through Necroptosis and Immune Response.
1/2024	Synthesis and anticancer mechanisms of four novel platinum(II) 4'-substituted-2,2':6',2''-terpyridine complexes.
12/2023	8-hydroxyquinoline-N-oxide copper(II)- and zinc(II)-phenanthroline and bipyridine coordination compounds: Design, synthesis, structures, and antitumor evaluation.
1/2023	Designing a multitarget In(III) compound to overcome the resistance of lung cancer cells to cisplatin.
1/2023	In vitro and in vivo antitumor activities of Ru and Cu complexes with terpyridine derivatives as ligands.
1/2023	Platinum(II) 5-substituted-8-hydroxyquinoline coordination compounds induces mitophagy-mediated apoptosis in A549/DDP cancer cells.
3/2022	Design of a novel Pt(II) complex to reverse cisplatin-induced resistance in lung cancer via a multi-mechanism.
3/2022	Complexes of Zn(II) with a mixed tryptanthrin derivative and curcumin chelating ligands as new promising anticancer agents.
2/2022	Terpyridine copper(II) complexes as potential anticancer agents by inhibiting cell proliferation, blocking the cell cycle and inducing apoptosis in BEL-7402 cells.
1/2022	Developing a Copper(II) Agent Based on His-146 and His-242 Residues of Human Serum Albumin Nanoparticles: Integration To Overcome Cisplatin Resistance and Inhibit the Metastasis of Nonsmall Cell Lung Cancer.

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Hong Liang Research Topics

Disease

188	Neoplasms (Cancer) 05/2024 - 07/2002
20	Inflammation (Inflammations) 04/2024 - 01/2002
18	Breast Neoplasms (Breast Cancer) 12/2022 - 07/2012
15	Mitochondrial Diseases (Mitochondrial Disease) 01/2024 - 03/2015
14	Neoplasm Metastasis (Metastasis) 03/2024 - 11/2012
10	Infections 01/2024 - 04/2015
9	Lung Neoplasms (Lung Cancer) 04/2024 - 10/2012
9	Hypoxia (Hypoxemia) 02/2024 - 10/2011
9	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 03/2023 - 04/2012
9	Glioma (Gliomas) 11/2022 - 10/2011
8	Carcinoma (Carcinomatosis) 01/2022 - 01/2009
7	Glaucoma 01/2023 - 12/2004
7	Dry Eye Syndromes (Dry Eye Syndrome) 10/2022 - 10/2005
6	Pain (Aches) 02/2023 - 03/2007
6	COVID-19 01/2023 - 01/2021
6	Hepatocellular Carcinoma (Hepatoma) 01/2023 - 01/2009
6	Colorectal Neoplasms (Colorectal Cancer) 04/2022 - 01/2017
6	Keshan disease 12/2021 - 01/2019
6	Tuberculosis (Tuberculoses) 01/2021 - 10/2010
5	Wounds and Injuries (Trauma) 10/2022 - 01/2012
5	Leukemia 01/2021 - 10/2007
5	Alzheimer Disease (Alzheimer's Disease) 12/2020 - 01/2015
4	Cystinosis 09/2022 - 01/2017
4	Obesity 06/2022 - 12/2017
4	Urinary Bladder Neoplasms (Bladder Cancer) 04/2022 - 10/2019
4	Hypoglycemia (Reactive Hypoglycemia) 01/2022 - 02/2011
4	Malaria 01/2020 - 04/2011
4	Liver Neoplasms (Liver Cancer) 01/2016 - 02/2011
3	Human Influenza (Influenza) 04/2024 - 12/2016
3	Triple Negative Breast Neoplasms 03/2024 - 09/2018
3	Pediatric Obesity 12/2023 - 06/2022
3	Parkinson Disease (Parkinson's Disease) 11/2023 - 07/2004
3	Residual Neoplasm 02/2023 - 11/2012
3	Adenocarcinoma of Lung 01/2023 - 12/2014

Drug/Important Bio-Agent (IBA)

37	Cisplatin (Platino)FDA LinkGeneric 03/2024 - 06/2010
29	Proteins (Proteins, Gene)FDA Link 04/2024 - 10/2008
19	CopperIBA 03/2024 - 03/2015
15	MetalsIBA 03/2024 - 02/2012
15	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2024 - 01/2015
14	LigandsIBA 01/2023 - 01/2009
13	AntigensIBA 05/2024 - 10/2008
13	Human Serum Albumin FDA LinkGeneric 03/2024 - 03/2015
13	PlatinumIBA 11/2023 - 06/2013
12	1-phenyl-3,3-dimethyltriazene (PDT)IBA 02/2024 - 10/2014
12	Biomarkers (Surrogate Marker)IBA 12/2023 - 07/2012
9	ThiosemicarbazonesIBA 03/2024 - 01/2018
9	Hyaluronic Acid (Hyaluronan)IBA 02/2024 - 01/2002
9	CarbonIBA 02/2023 - 10/2014
9	VaccinesIBA 01/2022 - 07/2011
8	Hydroxyl RadicalIBA 01/2024 - 11/2021
8	Glutathione (Reduced Glutathione)IBA 11/2023 - 11/2021
8	Glucose (Dextrose)FDA LinkGeneric 01/2022 - 02/2011
7	Antineoplastic Agents (Antineoplastics)IBA 12/2023 - 01/2016
7	Telomerase (Telomerase Reverse Transcriptase)IBA 12/2019 - 03/2015
6	ProdrugsIBA 11/2023 - 10/2015
6	Peptides (Polypeptides)IBA 01/2023 - 07/2013
5	SolutionsIBA 02/2024 - 07/2011
5	Hydrogen Peroxide (Hydroperoxide)FDA LinkGeneric 01/2024 - 11/2020
5	CytokinesIBA 12/2023 - 12/2004
5	LipidsIBA 01/2022 - 05/2016
5	EnzymesIBA 01/2022 - 04/2016
5	Oxygen (Dioxygen)IBA 01/2022 - 11/2017
5	Carrier Proteins (Binding Protein)IBA 12/2021 - 06/2010
4	IonsIBA 05/2024 - 01/2023
4	PolymersIBA 02/2023 - 01/2020
4	Liposomes (Liposome)IBA 01/2023 - 01/2019
4	EmulsionsIBA 01/2023 - 08/2009
4	Latanoprost (Xalatan)FDA Link 01/2023 - 01/2008
4	Cystine (L-Cystine)IBA 09/2022 - 01/2017
4	DNA (Deoxyribonucleic Acid)IBA 03/2022 - 01/2018
4	Therapeutic UsesIBA 01/2022 - 09/2018
4	Indicators and Reagents (Reagents)IBA 01/2022 - 10/2012
4	PhosphatidylserinesIBA 12/2021 - 10/2011
4	GoldIBA 12/2021 - 01/2018
4	Cytochromes c (Cytochrome c)IBA 10/2020 - 01/2017
4	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2012 - 11/2006
3	AntioxidantsIBA 04/2024 - 01/2011
3	isoquinolineIBA 03/2024 - 01/2017
3	Messenger RNA (mRNA)IBA 03/2024 - 04/2012
3	nasIBA 02/2024 - 05/2019
3	Adenosine Triphosphate (ATP)IBA 01/2024 - 01/2019
3	Lanthanoid Series Elements (Lanthanides)IBA 12/2023 - 03/2011
3	Photosensitizing Agents (Photosensitizers)IBA 12/2023 - 05/2018
3	ApoferritinsIBA 11/2023 - 11/2020
3	plumbaginIBA 11/2023 - 03/2011
3	Benzalkonium Compounds (Benzalkonium Chloride)FDA LinkGeneric 01/2023 - 10/2008
3	Amino Acids FDA Link 01/2023 - 07/2019
3	Ophthalmic Solutions (Eye Drops)IBA 01/2023 - 06/2011
3	Hemoglobins (Hemoglobin)IBA 01/2023 - 01/2019

Therapy/Procedure

59	Therapeutics 04/2024 - 10/2008
16	Drug Therapy (Chemotherapy) 11/2023 - 06/2010
13	Photothermal Therapy 12/2023 - 10/2014
12	Phototherapy (Light Therapy) 02/2024 - 11/2014
11	Lasers (Laser) 12/2023 - 05/2015
7	Precision Medicine 03/2024 - 05/2018
7	Photochemotherapy (Photodynamic Therapy) 02/2024 - 10/2014
6	Immunotherapy 05/2024 - 11/2017
6	Length of Stay 08/2022 - 02/2011
3	Chinese Traditional Medicine (Traditional Chinese Medicine) 04/2024 - 08/2008
3	Activities of Daily Living (ADL) 01/2024 - 03/2007